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Silent stroke in patients with transient ischemic attack or minor ischemic stroke. The Dutch TIA Trial Study Group

机译：短暂性脑缺血发作或轻度缺血性脑卒中的患者无声中风。荷兰TIA试用研究小组

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BACKGROUND AND PURPOSE: We studied silent stroke (i.e., infarcts on computed tomographic scan not related to later symptoms) in patients after transient ischemic attack or minor ischemic stroke. METHODS: Ours is a cross-sectional study of 2,329 patients who were randomized in a secondary prevention trial after transient ischemic attack or minor ischemic stroke and had no residual deficit after the qualifying event. RESULTS: Silent stroke was observed in 13% of the 2,329 patients. Lacunes formed 79%, cortical lesions 14%, and border zone lesions 7% of all silent strokes. Silent lacunes were most often located in the basal ganglia and symptomatic lacunes most often in the corona radiata. Age, hypertension, and current cigarette smoking were related to the presence of silent stroke. Silent stroke was equally common in different types of transient ischemic attack, including transient monocular blindness. Residual symptoms of any kind were more common in patients with silent stroke than in those without. CONCLUSIONS: Because only the sites of silent stroke infarcts differed slightly from those of symptomatic infarcts and the frequency of vascular risk factors was similar to that of symptomatic infarcts, silent stroke may have the same bearing on future risk as known prior stroke
机译：背景与目的：我们研究了短暂性脑缺血发作或轻度缺血性脑卒中后患者的无声中风（即，计算机断层扫描的梗塞与以后的症状无关）。方法：我们是一项横断面研究，对2329例患者进行了横断面研究，这些患者在短暂性脑缺血发作或轻度缺血性脑卒中后进行了二级预防试验，并且在排位赛后没有残留缺陷。结果：在2329名患者中，有13％观察到了中风。在所有无声中风中，腔隙形成了79％，皮质病变为14％，边界区病变为7％。沉默的腔室最常位于基底神经节，而有症状的腔室最常位于电晕辐射中。年龄，高血压和当前吸烟与无声中风有关。沉默性中风在不同类型的短暂性脑缺血发作中同样普遍，包括短暂性单眼失明。无症状中风的患者比没有无症状的患者更常见任何形式的残留症状。结论：由于仅沉默性中风的部位与症状性梗死的部位略有不同，并且血管危险因素的频率与症状性梗死的频率相似，所以沉默性中风可能对未来风险的影响与已知的先前中风相同

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